Describe the evidence presented in the paper you selected. Specifically address the following questions:-What is the issue addressed in the paper?- What was the exposure or intervention?-What was the outcome?-What was the study design?-What was the study population?-What were the main findings? QUESTION 2:Do you think there is evidence of a causal association between the exposure and the outcome? This question relates to the internal validity of the study. Consider the following questions in your critique:-Is there a temporal relationship between exposure and outcome?-Is there a strong relationship between the exposure and the outcome? -Is there a dose-response relationship between exposure and the outcome?-Are the results consistent within the study? QUESTION 3:To what extent can the observed association between the exposure and outcome be attributed to non-causal explanations? Consider the following questions in your critique:-Are the results likely to be affected by selection and/or measurement bias?-Are the results likely to be affected by confounding?-Are the results likely to be affected by chance variation?QUESTION 4:Do the findings accord with other evidence? Specifically: -Are the findings consistent with other evidence, particularly evidence from studies of similar or more powerful study design? -Are the results plausible in terms of a biological mechanism?QUESTION 5:Are the findings externally valid, that is generalisable? Specifically:-Can the findings be applied to the source population from which the study population was derived?-Can the study results be applied to other relevant populations?
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