Category: Essays

Study objectives To evaluate the diagnostic value of established Malnutrition Universal Screening Tool (MUST)1-3 in NET patients
To achieve management guidelines for NET patients with low, medium and high risk of malnutrition
Aim to improve the MUST score1-3 of NET patients with use of biomarkers i-e Cg A and bile acid mal absorption tests4-5 i-e faecal elastase, SeHCAT test etc.
Study design: Cohort Study
Planned subject number Study: 50 patients with gastrointestinal or pancreatic (GEP) NET: this will include treatment genuine patients and patients who have received an intervention (i.e. surgery and/or treatment with somatostatin therapy). Subgroup analysis between functional and non-functional tumours will be done based on clinical symptoms.
Controls: patients without NET who are screened for malabsorption in Gastroenterology outpatient clinics (OPCs)
Schedule of visits and assessments Study patients will be screened as part of pre consultation assessment at outpatient NET clinic visits in order to detect possible risk of malnutrition and to suggest further diagnostic and treatment pathways. Food intake and nutritional data will be collected as part of clinical history taking.

Validation of MUST score1-3 measurements on another established similar cohort of NET patients
Diagnosis and main criteria for inclusion and exclusion Subjects with known NET disease will be screened

Main inclusion criteria: Both genders, signed informed consent. histologically confirmed diagnosis of NET; or strong suspicion of NET using combination of clinical presentation, radiological findings including octreotide or gallium scan; and biomarkers
Main exclusion criteria: Pregnancy, Unwell patients, Unable to measure height or weight, medications influencing appetite
Evaluated product: dose/mode of admin/ dosing schedule 1. Body Mass Index
2. Weight loss
3. Acute disease effect Score
Reference therapy: dose/ mode of admin/dosing schedule Stratify patients between Score 0 (low), 1 (medium) or 2 or more (high risk) of malnutrition
Primary target variables Improvement of sensitivity and accuracy of established nutritional screening test in patients with Neuroendocrine (NET) disease.
Secondary target variables Establish a modified MUST score specifically for NET patients
Statistical methods
Standard statistical methods (ANOVA, GLM, T-tests for subgroup analyses). Sensitivity, specificity and efficacy assessment ( positive predictive value, negative predictive value)

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Research methodology can help to define the activities of research, how to proceed with the research, how to measure progress and how to determine success. This week you explored how different epistemologies relate to particular research methodologies and the highlights of some methodologies in use today. In this Discussion you will evaluate existing methodologies and explore the methodology that you will use for your dissertation.

To prepare for this Discussion, identify two or three journal articles that address research problems similar to the problem you have chosen in your dissertation proposal, and evaluate the methodology used to conduct the research. (You find the dissertation proposal attached.)

With these thoughts in mind, in a 750-1,000 word response – stay very focussed, use at least 10 ‘new’ peer-viewed articles, use Harvard referencing:

• How has your problem or question been studied in the past?
• What methodology would be most useful in addressing your research problem or question?

Defend your choice of methodology. Discuss whether you would use a research design and approach similar to those you reviewed, or approach your problem differently and why.

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This is coursework is about the building project management and procurement.
Preamble:You are a Client on a £44m building project. You have appointed your Design Team and have a budget threshold and deadline that you have stated to your Design Team must not be exceeded. As an experienced Client you have held back budget and some weeks in reserve that you have not declared to your Design Team.
The Architect is playing the traditional role of Lead Designer and Design Team Leader
To complete this assignment you are required to research and set out each Stage of the RIBA Plan of Work 2013 (0-7). More detail will be uploaded. Please do follow the questions to complete this assignment.

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#First essay is about ( Religion and religious issues in colonial American history )
It SHOULD be about 5-7 paragraphs.

#Second essay is about ( The importance of immigration / Trans-atlantic slave trade )

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Use book operation chain supply management Author F. Robert Jacobs and Richard B Chase. case study on page 21.a comparison of the five common measures of efficiency use by Wall Street. Pick an industry select three companies research their rating on the five measures and put together an analysis and recommend one of the three as a company you would invest in. Can’t use the three companies although you can select the industry used if you choose. example in chapter one used. industry auto.not the three companies This was the case at the end of chapter one. do analysis about assets between business which better investment and stock price, total asst, turn over, revenue.

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The case study should view leaders and organizations in a global and dynamic environment that tests the viability of the company Alibaba. The case will deal with a leadership issue related to the viability of the Alibaba in a global, dynamic environment. Your approach to Alibaba will involve a leadership inquiry.
Your case study must:
1. Focus on a leadership issue, opportunity, practice, and theory.
2. Link leadership and firm viability.
3. Be situated in a global environment.
4. Focus on a leadership issue or concern that crosses systems and cultures.
5. Integrate theory and practice.
6. Engage your intellectual curiosity.
7. Be well-written.
8. Be presented creatively using multimedia, involving both audio and visual components.
Note: This case study must be based solely on public secondary material and available peer-reviewed sources. There will be no primary research through use of such activities as interviews, use of instruments, and so on.
There should be a minimum of 15 annotated references with at least 10 of them related to the appropriate leadership theory for the case. The remaining references may include practitioner pieces and web or video links.

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Topics to choose from: Ancient Greece, Roman Empire, Paleolithic Age, Ancient Mesopotamia or Byzantium Empire

People, eras, and events covered in this class also influenced today’s world. Select one person, event, or era from the material in this course–excluding the barbarians–that had the most significant effect on the world today. Write a 1,050- to 1,250-word research paper in which you address the following:
•Describe the person, era, or event and explain its significance
•How did your chosen person, event, or era change the course of history?
•How did your chosen person, event, or era affect today’s world?
•Do not speculate. Do not try to predict what might be different without your chosen person, era, or event. Stick to what did happen, why it happened, why it is significant, and/or what it means to today’s world.

Format your paper consistent with APA guidelines. Submit your paper as a Microsoft Word document.

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Use the PPSA structure to write to me about a problem with the Job App. Package – and tell me your solution: what can I do to improve the JAP to make it more helpful for future students. For example, are there specific issues/challenges that you faced? Are there issues in Qatar/the Middle East that make the JAP problematic/too challenging/unrealistic/etc? Use the PPSA to first outline your ideas, then use it again to write the memo.

first paragraph: purpose
second paragraph: problem
third paragraph: solution
fourth paragraph: action

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Argue how Whitman’s style of writing has changed in the poem Crossing Brooklyn Ferry (1856 Leaves of Grass) and another poem after 1860 i.e. Lilacs Bloom or Wound Dresser because of the Civil War. Make sure this is not an analysis that gives introduction to Whitman’s birth date, where he was born, or any other survey introduction to Whitman. Make sure this is a strong thesis paper that explains why within Brooklyn Ferry and the other poem of a later edition, is written by almost 2 different Whitmans because of the Civil War. Whitman is not to be described as a heterosexual/political activist. He may have strong emotions attached to political events.
Do not use Songs of Myself, preferably use Lilacs Bloom or Wound Dresser. Compare the Leaves of Grass edition 1856 and anything after 1860. Make sure to use textual evidence in any statements used. Please do not use sophisticated diction; rather, write this essay with humble diction and a tone of an earnest undergraduate. Please do however, make sure this is a strong thesis essay. I will attach a file of my own writing style and another paper of a bad writing style to give you examples of this.

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Create a summary of the reading.In this paper please include the purpose of the research, what was studied, what results were gained( if any), and a conclusion. while retaining important concepts, key words, and important data. Please include atleast three quotes directly form the article (site page number). the last paragraph should be on what you enjoyed or did not enjoy from the article.

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