The mechanism and efficiency of ECULIZUMAB drug in paroxysmal nocturnal haemoglobinuria patient. Custom Essay

Start define the paroxysmal nocturnal haemoglobinuria patient. and ( related to complement) and write the the outcomes like Paroxysmal nocturnal haemoglobinuria (PNH) is characterized by chronic, uncontrolled complement activation resulting in elevated intravascular haemolysis and morbidities, including fatigue, dyspnoea, abdominal pain, pulmonary hypertension, thrombotic events (TEs) and chronic kidney disease (CKD). Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, progressive and life-threatening haematopoietic stem cell disorder. It is characterized by complement-mediated intravascular haemolysis and a prothrombotic state (Brodsky, 2009; Hillmen et al, 2010). talk about ECULIZUMAB as a new treatment that inhibit paroxysmal nocturnal haemoglobinuria patient. How to inhibit paroxysmal nocturnal haemoglobinuria patient ( block the C5 complement)

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